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Found 39 records
Species:
Canine
System:
Multisystem
Disease Condition:
Actinomycosis
Antimicrobial(s):
1. Amoxicillin (20-40 mg/kg PO q6-8h)
Alternatives:
2. Erythromycin (10 mg/kg PO q8h) or
3. Clindamycin (5-10 mg/kg PO q12h) or
4. Doxycycline (5-10 mg/kg P q12h) or
5. Chloramphenicol (40-50 mg/kg PO q8h)
Alternatives:
2. Erythromycin (10 mg/kg PO q8h) or
3. Clindamycin (5-10 mg/kg PO q12h) or
4. Doxycycline (5-10 mg/kg P q12h) or
5. Chloramphenicol (40-50 mg/kg PO q8h)
VDD Category:
1. II
2. II
3. II
4. III
5. III
2. II
3. II
4. III
5. III
Species:
Canine
System:
Reproductive
Disease Condition:
Acute prostatitis
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg PO q24h or
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
6. Clindamycin (for confirmed susceptible infections) 10-15 mg/kg PO/IV q12h
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
6. Clindamycin (for confirmed susceptible infections) 10-15 mg/kg PO/IV q12h
VDD Category:
1. I
2. I
3. I
4. I
5. II
6. II
2. I
3. I
4. I
5. II
6. II
Species:
Canine
System:
Neurological
Disease Condition:
Bacterial meningitis
Antimicrobial(s):
1. Enrofloxacin: 20 mg/kg PO q24h or
2. Marbofloxacin: 5.5 mg/kg PO q24h or
3. Orbifloxacin: 7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Cefotaxime (20-50 mg/kg IV q6-8h)
2. Marbofloxacin: 5.5 mg/kg PO q24h or
3. Orbifloxacin: 7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Cefotaxime (20-50 mg/kg IV q6-8h)
VDD Category:
1. I
2. I
3. I
4. I
5. I
2. I
3. I
4. I
5. I
Species:
Canine
System:
Multisystem
Disease Condition:
Bartonellosis
Antimicrobial(s):
1. Doxycycline (5-10 mg/kg PO q12h)
Alternatives:
2. Azithromycin (10 mg/kg PO q24h) or
3. Enrofloxacin: 10-20 mg/kg PO q24h or
4. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
5. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
6. Pradofloxacin: 3-5 mg/kg PO q24h or
7. Amoxicillin/clavulanic acid (12.5-20 mg/kg PO q12h)
Alternatives:
2. Azithromycin (10 mg/kg PO q24h) or
3. Enrofloxacin: 10-20 mg/kg PO q24h or
4. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
5. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
6. Pradofloxacin: 3-5 mg/kg PO q24h or
7. Amoxicillin/clavulanic acid (12.5-20 mg/kg PO q12h)
VDD Category:
1. III
2. II
3. I
4. I
5. I
6. I
7. I
2. II
3. I
4. I
5. I
6. I
7. I
Species:
Canine
System:
Respiratory
Disease Condition:
Bronchitis
Antimicrobial(s):
If treatment is indicated:
1. Doxycycline: 5 mg/kg PO q12h or 10 mg/kg PO q24h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
1. Doxycycline: 5 mg/kg PO q12h or 10 mg/kg PO q24h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
VDD Category:
1. III
2. I
2. I
Species:
Canine
System:
Reproductive
Disease Condition:
Brucellosis
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg PO q24h or
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
Ideally in combination with
5. Doxycycline 5 mg/kg PO q12h
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
Ideally in combination with
5. Doxycycline 5 mg/kg PO q12h
VDD Category:
1. I
2. I
3. I
4. I
5. III
2. I
3. I
4. I
5. III
Species:
Canine
System:
Gastrointenstinal
Disease Condition:
Campylobacteriosis
Antimicrobial(s):
1. Erythromycin 10-15 mg/kg q8h
Alternatives:
2. Azithromycin 5-10 mg/kg PO q24h or
3. Tylosin 11 mg/kg PO q8h or
4. Enrofloxacin: 10 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h
Uncommonly used:
8. Chloramphenicol 25-50 mg/kg PO q8h
Alternatives:
2. Azithromycin 5-10 mg/kg PO q24h or
3. Tylosin 11 mg/kg PO q8h or
4. Enrofloxacin: 10 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h
Uncommonly used:
8. Chloramphenicol 25-50 mg/kg PO q8h
VDD Category:
1. II
2. II
3. II
4. I
5. I
6. I
7. I
8. III
2. II
3. II
4. I
5. I
6. I
7. I
8. III
Species:
Canine
System:
Respiratory
Disease Condition:
Canine infectious respiratory disease complex
Antimicrobial(s):
If <10d duration with no evidence of pneumonia:
None
If >10d duration and fever, lethargy or inappetence, plus muocpurulent discharge are present:
1. Doxycycline: 5 mg/kg PO q12h or 10 mg/kg PO q24h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
None
If >10d duration and fever, lethargy or inappetence, plus muocpurulent discharge are present:
1. Doxycycline: 5 mg/kg PO q12h or 10 mg/kg PO q24h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
VDD Category:
1. III
2. I
2. I
Species:
Canine
System:
Reproductive
Disease Condition:
Chronic prostatitis
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg PO q24h or
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
6. Clindamycin (for confirmed susceptible infections) 10-15 mg/kg PO/IV q12h
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
6. Clindamycin (for confirmed susceptible infections) 10-15 mg/kg PO/IV q12h
VDD Category:
1. I
2. I
3. I
4. I
5. II
6. II
2. I
3. I
4. I
5. II
6. II
Species:
Canine
System:
Skin
Disease Condition:
Deep pyoderma
Antimicrobial(s):
1. Clindamycin: 5.5 mg/kg PO q12h or
2. Cephalexin: 15-30 mg/kg PO q12h or
3. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
2. Cephalexin: 15-30 mg/kg PO q12h or
3. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
VDD Category:
1. II
2. II
3. I
2. II
3. I
Species:
Canine
System:
Dental
Disease Condition:
Dental abscess
Antimicrobial(s):
Usually none.
If required:
1. Clindamycin: 11-22 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-20 mg/kg PO q12h.
If required:
1. Clindamycin: 11-22 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-20 mg/kg PO q12h.
VDD Category:
1. II
2. I
2. I
Species:
Canine
System:
Dental
Disease Condition:
Dental extractions
Antimicrobial(s):
Usually none, unless there are patient factors that predispose to systemic infection, if there is marked involvement of local soft tissues or if there is concurrent involvement of bone.
If needed:
1. Ampicillin: 20-40 mg/kg IV, 30-60 minutes prior to the procedure and every 90 minutes until the procedure is done, or
2. Clindamycin: 11-22 mg/kg IV, single dose, 1 hr before the procedure, or
3. Cefazolin: 20-22 mg/kg, IV 30-60 minutes before the procedure.
Post-procedure antimicrobials are not required for prophylaxis. Continued antimicrobials are indicated for treatment of concurrent soft tissue (5-7d) or bone (28d) involvement.
If needed:
1. Ampicillin: 20-40 mg/kg IV, 30-60 minutes prior to the procedure and every 90 minutes until the procedure is done, or
2. Clindamycin: 11-22 mg/kg IV, single dose, 1 hr before the procedure, or
3. Cefazolin: 20-22 mg/kg, IV 30-60 minutes before the procedure.
Post-procedure antimicrobials are not required for prophylaxis. Continued antimicrobials are indicated for treatment of concurrent soft tissue (5-7d) or bone (28d) involvement.
VDD Category:
1. II
2. II
3. II
2. II
3. II
Species:
Canine
System:
Dental
Disease Condition:
Dental prophylaxis
Antimicrobial(s):
Rarely required.
If needed:
1. Ampicillin: 20-40 mg/kg IV, 30-60 minutes prior to the procedure and every 90 minutes until the procedure is done, or
2. Clindamycin: 11-22 mg/kg IV, single dose, 1 hr before the procedure, or
3. Cefazolin: 20-22 mg/kg, IV 30-60 minutes before the procedure.
If needed:
1. Ampicillin: 20-40 mg/kg IV, 30-60 minutes prior to the procedure and every 90 minutes until the procedure is done, or
2. Clindamycin: 11-22 mg/kg IV, single dose, 1 hr before the procedure, or
3. Cefazolin: 20-22 mg/kg, IV 30-60 minutes before the procedure.
VDD Category:
1. II
2. II
3. II
2. II
3. II
Species:
Canine
System:
Neurological
Disease Condition:
Diskospondylitis
Antimicrobial(s):
1. Amoxicillin/clavulanic acid (12.5-20 mg/kg PO q12h)
Depending on culture/serology results:
2. Cephalexin (15-30 mg/kg PO q12h) or
3. Clindamycin (10-30 mg/kg PO q12h) or
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 5.5 mg/kg PO q24h or
6. Orbifloxacin: 7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h
If Brucella canis is involved:
8. Enrofloxacin: 10-20 mg/kg PO q24h or
9. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
10. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
11. Pradofloxacin: 3-4.5 mg/kg PO q24h or
Ideally in combination with:
12. Doxycycline 5 mg/kg PO q12h
Depending on culture/serology results:
2. Cephalexin (15-30 mg/kg PO q12h) or
3. Clindamycin (10-30 mg/kg PO q12h) or
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 5.5 mg/kg PO q24h or
6. Orbifloxacin: 7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h
If Brucella canis is involved:
8. Enrofloxacin: 10-20 mg/kg PO q24h or
9. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
10. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
11. Pradofloxacin: 3-4.5 mg/kg PO q24h or
Ideally in combination with:
12. Doxycycline 5 mg/kg PO q12h
VDD Category:
1. II
2. II
3. II
4. I
5. I
6. I
7. I
8. I
9. I
10. I
11. I
12. III
2. II
3. II
4. I
5. I
6. I
7. I
8. I
9. I
10. I
11. I
12. III
Species:
Canine
System:
Gastrointenstinal
Disease Condition:
Helicobacter spp infection
Antimicrobial(s):
1. Metronidazole (11-15 mg/kg PO q12) + amoxicillin (22 mg/kg PO q12h) + bismuth subsalicylate suspension (0.22 mg/kg po q6-8h) or
2. Clarithromycin (7.5 mg./kg PO q12h) + amoxicillin (22 mg/kg PO q12h) + proton pump inhibitor or
3. Clarithromycin (7.5 mg./kg PO q12h) + amoxicillin (22 mg/kg PO q12h) + metronidazole (10 mg/kg PO q12h).
2. Clarithromycin (7.5 mg./kg PO q12h) + amoxicillin (22 mg/kg PO q12h) + proton pump inhibitor or
3. Clarithromycin (7.5 mg./kg PO q12h) + amoxicillin (22 mg/kg PO q12h) + metronidazole (10 mg/kg PO q12h).
VDD Category:
1. I/II
2. II/II
3. II/II/I
2. II/II
3. II/II/I
Species:
Canine
System:
Other/Multisystem
Disease Condition:
Hemotropic Mycoplasma
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg PO q24h or
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Doxycycline (5 mg/kg PO q12h or 10 mg/kg PO q24h)
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h or
5. Doxycycline (5 mg/kg PO q12h or 10 mg/kg PO q24h)
VDD Category:
1. I
2. I
3. I
4. I
5. III
2. I
3. I
4. I
5. III
Species:
Canine
System:
Other/Multisystem
Disease Condition:
Leptospirosis
Antimicrobial(s):
If oral drugs are tolerated:
1. Doxycycline: 5 mg/kg PO q12h
If oral medications cannot be given:
2. Doxycycline: 5 mg/kg IV q12h or
3. Ampicillin: 20 mg/kg IV q6h.
1. Doxycycline: 5 mg/kg PO q12h
If oral medications cannot be given:
2. Doxycycline: 5 mg/kg IV q12h or
3. Ampicillin: 20 mg/kg IV q6h.
VDD Category:
1. III
2. III
3. II
2. III
3. II
Species:
Canine
System:
Other/Multisystem
Disease Condition:
Lyme disease
Antimicrobial(s):
1. Doxycycline 10 mg/kg PO q24h
VDD Category:
1. III
Species:
Canine
System:
Multisystem
Disease Condition:
Nocardiosis
Antimicrobial(s):
1. Trimethoprim-sulfonamide (15-30 mg/kg PO q12h)
Alternatives:
2. Cefpodoxime (5-10 mg/kg P q24h) or
3. Amoxicillin (20 mg/kg PO q6-8h) or
4. Doxycycline (5-10 mg/kg PO q12h) or
5. Amikacin (20 mg/kg IV/IM/SQ q24h)
Alternatives:
2. Cefpodoxime (5-10 mg/kg P q24h) or
3. Amoxicillin (20 mg/kg PO q6-8h) or
4. Doxycycline (5-10 mg/kg PO q12h) or
5. Amikacin (20 mg/kg IV/IM/SQ q24h)
VDD Category:
1. II
2. I
3. II
4. III
5. II
2. I
3. II
4. III
5. II
Species:
Canine
System:
Multisystem
Disease Condition:
Non-tuberculous Mycobacterium infection
Antimicrobial(s):
Mycobacterium avium complex (MAC):
1. Clarithromycin (7.5-15 mg/kg PO q24h) + rifampin (10-15 mg/kg PO q24h) + doxycycline (5-10 mg/kg PO q12h) or
2. Clofazimine (4-8 mg/kg PO q24h) + rifampin (10-15 mg/kg PO q24h) + doxycycline(5-10 mg/kg PO q12h)
3. A fluoroquinolone or amikacin (20 mg/kg IV/IM/SC) can be added or used to lieu of individual drugs above.
Non-MAC:
4. Fluoroquinolone *
+
5. Either clarithromycin (7.5-15 mg/kg PO q12h) or azithromycin (5-15 mg/kg PO q24h)
+
6. Rifampin (10-15 mg/kg PO q24h)
1. Clarithromycin (7.5-15 mg/kg PO q24h) + rifampin (10-15 mg/kg PO q24h) + doxycycline (5-10 mg/kg PO q12h) or
2. Clofazimine (4-8 mg/kg PO q24h) + rifampin (10-15 mg/kg PO q24h) + doxycycline(5-10 mg/kg PO q12h)
3. A fluoroquinolone or amikacin (20 mg/kg IV/IM/SC) can be added or used to lieu of individual drugs above.
Non-MAC:
4. Fluoroquinolone *
+
5. Either clarithromycin (7.5-15 mg/kg PO q12h) or azithromycin (5-15 mg/kg PO q24h)
+
6. Rifampin (10-15 mg/kg PO q24h)
VDD Category:
1. II/I/III
2. NR/I/III
3. I/II
4. I
5. II
6. I
2. NR/I/III
3. I/II
4. I
5. II
6. I
Species:
Canine
System:
Derm
Disease Condition:
Otitis externa
Antimicrobial(s):
Topical therapy only, typically with a product containing an antimicrobial, antifungal and anti-inflammatory
VDD Category:
N/A
Species:
Canine
System:
Gastrointenstinal
Disease Condition:
Parvoviral enteritis
Antimicrobial(s):
1. Ceftiofur sodium: 2.2 mg/kg SC/IM/IV q12h or
2. Cefoxitin: 15-30 mg/kg IV q6-8h
2. Cefoxitin: 15-30 mg/kg IV q6-8h
VDD Category:
1. I
2. II
2. II
Species:
Canine
System:
Multisystem
Disease Condition:
Plague
Antimicrobial(s):
1. Doxycycline (5-10 mg/kg PO q12h) or
2. Streptomycin (5 mg/kg IM q12h) or
3. Gentamicin (6-8 mg/kg IV/IM/SQ q24h) or
4. Chloramphenicol (50 mg/kg PO q8h)
2. Streptomycin (5 mg/kg IM q12h) or
3. Gentamicin (6-8 mg/kg IV/IM/SQ q24h) or
4. Chloramphenicol (50 mg/kg PO q8h)
VDD Category:
1. III
2. II
3. II
4. III
2. II
3. II
4. III
Species:
Canine
System:
Respiratory
Disease Condition:
Pneumonia with systemic disease/sepsis
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg IM/IV q24h
COMBINED WITH EITHER
2. Ampicillin: 22-30 mg/kg IV/SQ q8h) or
3. Clindamycin: 10-15 mg/kg IV q12h
COMBINED WITH EITHER
2. Ampicillin: 22-30 mg/kg IV/SQ q8h) or
3. Clindamycin: 10-15 mg/kg IV q12h
VDD Category:
1. I
2. II
3. II
2. II
3. II
Species:
Canine
System:
Respiratory
Disease Condition:
Pneumonia without systemic disease
Antimicrobial(s):
1. Doxycycline: 5 mg/kg PO q12h or 10 mg/kg PO q24h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
If Streptococcus zooepidemicus is known to be, or is likely, the cause:
3. Amoxicillin: 22 mg/kg PO q8-12h
If doxycycline is contraindicated in the dog:
2. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
If Streptococcus zooepidemicus is known to be, or is likely, the cause:
3. Amoxicillin: 22 mg/kg PO q8-12h
VDD Category:
1. III
2. I
3. II
2. I
3. II
Species:
Canine
System:
Urinary
Disease Condition:
Pyelonephritis
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg PO q24h or
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h
ALTERNATIVE TREATMENTS
5. Ceftiofur 2.2 mg/kg SC/IM/IV q12h
6. Cefotaxime (20-40 mg/kg IV q6-8h)
2. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
3. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
4. Pradofloxacin: 3-4.5 mg/kg PO q24h
ALTERNATIVE TREATMENTS
5. Ceftiofur 2.2 mg/kg SC/IM/IV q12h
6. Cefotaxime (20-40 mg/kg IV q6-8h)
VDD Category:
1. I
2. I
3. I
4. I
2. I
3. I
4. I
Species:
Canine
System:
Reproductive
Disease Condition:
Pyometra
Antimicrobial(s):
In patients with evidence of sepsis:
1. Ampicillin (20 mg/kg IV q6-8g) + enrofloxacin (10 mg/kg IV q24h) or
2. Cefotaxime (40 mg/kg IV q8h) or
3. Ceftiofur sodium (2.2 mg/kg IV q12h)
In stable patients undergoing hysterectomy:
4. Peri-operative administration of cefazolin (22 mg/kg IV 30-60 minutes before surgery and every 2 hours until the end of surgery. Can be continued for up to 24h, then stopped.
Medical (non-surgical) management of open pyometra, no evidence of sepsis:
5. Amoxicillin/clavulanic acid (12.5-20 mg/kg PO q12h) or
6. Enrofloxacin (10 mg/kg PO q24h) or
7. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
8. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
9. Pradofloxacin: 3-5 mg/kg PO q24h or
10. Cefpodoxime (5-10 mg/kg PO q24h)
1. Ampicillin (20 mg/kg IV q6-8g) + enrofloxacin (10 mg/kg IV q24h) or
2. Cefotaxime (40 mg/kg IV q8h) or
3. Ceftiofur sodium (2.2 mg/kg IV q12h)
In stable patients undergoing hysterectomy:
4. Peri-operative administration of cefazolin (22 mg/kg IV 30-60 minutes before surgery and every 2 hours until the end of surgery. Can be continued for up to 24h, then stopped.
Medical (non-surgical) management of open pyometra, no evidence of sepsis:
5. Amoxicillin/clavulanic acid (12.5-20 mg/kg PO q12h) or
6. Enrofloxacin (10 mg/kg PO q24h) or
7. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
8. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
9. Pradofloxacin: 3-5 mg/kg PO q24h or
10. Cefpodoxime (5-10 mg/kg PO q24h)
VDD Category:
1. II/I
2. I
3. I
4. II
5. I
6. I
7. I
8. I
9. I
10. I
2. I
3. I
4. II
5. I
6. I
7. I
8. I
9. I
10. I
Species:
Canine
System:
Respiratory
Disease Condition:
Pyothorax
Antimicrobial(s):
1. Enrofloxacin: 10-20 mg/kg IM/IV q24h
COMBINED WITH EITHER
2. Ampicillin: 22-30 mg/kg IV/SQ q8h) or
3. Clindamycin: 10-15 mg/kg IV q12h
COMBINED WITH EITHER
2. Ampicillin: 22-30 mg/kg IV/SQ q8h) or
3. Clindamycin: 10-15 mg/kg IV q12h
VDD Category:
1. I
2. II
3. II
2. II
3. II
Species:
Canine
System:
Urinary
Disease Condition:
Recurrent cystitis
Antimicrobial(s):
1. Amoxicillin: 11-15 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
ALTERNATIVE TREATMENT:
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h or
8. Cefpodoxime 5-10 mg/kg PO q24h or
9. Cephalexin 12-25 mg/kg PO q12h or
10. Cefovecin 8 mg/kg SC, single injection for 14d duration. Repeat if longer duration required
11. Nitrofurantoin 4.5-5 mg/kg PO q8h
12. Fosfomycin 40 mg/kg PO q12h
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
ALTERNATIVE TREATMENT:
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h or
8. Cefpodoxime 5-10 mg/kg PO q24h or
9. Cephalexin 12-25 mg/kg PO q12h or
10. Cefovecin 8 mg/kg SC, single injection for 14d duration. Repeat if longer duration required
11. Nitrofurantoin 4.5-5 mg/kg PO q8h
12. Fosfomycin 40 mg/kg PO q12h
VDD Category:
1. II
2. I
3. II
4. I
5. I
6. I
7. I
8. I
9. II
10. I
11. III
12. III
2. I
3. II
4. I
5. I
6. I
7. I
8. I
9. II
10. I
11. III
12. III
Species:
Canine
System:
Multisystem
Disease Condition:
Rocky Mountain Spotted Fever
Antimicrobial(s):
1. Doxycycline (5 mg/kg PO q12h)
VDD Category:
1. III
Species:
Canine
System:
Gastrointenstinal
Disease Condition:
Salmonellosis
Antimicrobial(s):
Evidence of Sepsis
1. Ceftiofur sodium 2.2mg/kg IV q12h
2. Amikacin 10-15 mg/kg IV q24h
Plus One Of
3. Ampicillin 22-30 mg/kg IV/SQ q8h
4. Clindamycin 10-15 mg/kg IV q12h
5. Cefotaxime 40-60 mg/kg IV q8h
If Oral Treatment Possible
6. Cefpodoxime 5-10 mg/kg PO q24h
1. Ceftiofur sodium 2.2mg/kg IV q12h
2. Amikacin 10-15 mg/kg IV q24h
Plus One Of
3. Ampicillin 22-30 mg/kg IV/SQ q8h
4. Clindamycin 10-15 mg/kg IV q12h
5. Cefotaxime 40-60 mg/kg IV q8h
If Oral Treatment Possible
6. Cefpodoxime 5-10 mg/kg PO q24h
VDD Category:
1. I
2. II
3. III
4. II
5. I
6. I
2. II
3. III
4. II
5. I
6. I
Species:
Canine
System:
Other/Multisystem
Disease Condition:
Skin/soft tissue abscess
Antimicrobial(s):
None.
If systemic disease or moderate/severe cellulitis is present consider:
1. Amoxicillin/clavulanic acid (12.5-25 mg/kg PO q12h for 3-7d).
If systemic disease or moderate/severe cellulitis is present consider:
1. Amoxicillin/clavulanic acid (12.5-25 mg/kg PO q12h for 3-7d).
VDD Category:
1. I
Species:
Canine
System:
Urinary
Disease Condition:
Sporadic cystitis
Antimicrobial(s):
RECOMMENDED TREATMENT:
1. Amoxicillin: 11-15 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
ALTERNATIVE TREATMENT:
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h or
8. Cefpodoxime 5-10 mg/kg PO q24h or
9. Cephalexin 12-25 mg/kg PO q12h or
10. Cefovecin 8 mg/kg SC, single injection
11. Nitrofurantoin 4.5-5 mg/kg PO q8h
12. Fosfomycin 40 mg/kg PO q12h
1. Amoxicillin: 11-15 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
ALTERNATIVE TREATMENT:
4. Enrofloxacin: 10-20 mg/kg PO q24h or
5. Marbofloxacin: 2.7-5.5 mg/kg PO q24h or
6. Orbifloxacin: 2.5-7.5 mg/kg PO q24h or
7. Pradofloxacin: 3-4.5 mg/kg PO q24h or
8. Cefpodoxime 5-10 mg/kg PO q24h or
9. Cephalexin 12-25 mg/kg PO q12h or
10. Cefovecin 8 mg/kg SC, single injection
11. Nitrofurantoin 4.5-5 mg/kg PO q8h
12. Fosfomycin 40 mg/kg PO q12h
VDD Category:
1. II
2. I
3. II
4. I
5. I
6. I
7. I
8. I
9. II
10. I
11. III
12. III
2. I
3. II
4. I
5. I
6. I
7. I
8. I
9. II
10. I
11. III
12. III
Species:
Canine
System:
Respiratory
Disease Condition:
Streptococcus zooepidemicus
Antimicrobial(s):
1. Amoxicillin 11-22 mg/kg PO q8h or
2. Clindamycin 5-10 mg/kg PO q12h
2. Clindamycin 5-10 mg/kg PO q12h
VDD Category:
1. II
2. II
2. II
Species:
Canine
System:
Urinary
Disease Condition:
Subclinical bacteriuria
Antimicrobial(s):
Usually none.
VDD Category:
N/A
Species:
Canine
System:
Skin
Disease Condition:
Superficial folliculitis
Antimicrobial(s):
Topical chlorhexidine (2%) bathing.
If bathing is not possible, one of the following can be used:
1. Clindamycin: 5.5 mg/kg PO q12h or
2. Cephalexin: 15-30 mg/kg PO q12h or
3. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
If bathing is not possible, one of the following can be used:
1. Clindamycin: 5.5 mg/kg PO q12h or
2. Cephalexin: 15-30 mg/kg PO q12h or
3. Amoxicillin-clavulanic acid: 12.5-25 mg/kg PO q12h
VDD Category:
1. II
2. II
3. I
2. II
3. I
Species:
Canine
System:
Skin
Disease Condition:
Superficial surgical site infection
Antimicrobial(s):
1. Amoxicillin/clavulanic acid, 12.5-20 mg/kg PO q12h or
2. Cephalexin 15-30 mg/kg PO q12h
2. Cephalexin 15-30 mg/kg PO q12h
VDD Category:
1. I
2. II
2. II
Species:
Canine
System:
Neurological
Disease Condition:
Tetanus
Antimicrobial(s):
1. Metronidazole (15-25 mg/kg IV or PO q8-12h) or
2. Ampicillin (20 mg/kg PO q8h)
2. Ampicillin (20 mg/kg PO q8h)
VDD Category:
1. I
2. II
2. II
Species:
Canine
System:
Urinary
Disease Condition:
Urolithiasis
Antimicrobial(s):
If evidence of active bacterial cystitis is present:
1. Amoxicillin: 11-15 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
1. Amoxicillin: 11-15 mg/kg PO q12h or
2. Amoxicillin/clavulanic acid: 12.5-25 mg/kg PO q12h or
3. Trimethoprim-sulfonamide (TMS): 15-30 mg/kg PO q12h
VDD Category:
1. II
2. I
3. II
2. I
3. II